美国成年人内脏脂肪指数,过早死亡率和预期寿命
Mei Xue1,2, Xiaoqian Zhang1,2, Kening Chen3,4
1Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Lipids in health and disease
|April 15, 2025
概括
较高的内脏脂肪指数 (VAI) 与美国成年人中早逝率增加和预期寿命缩短有关. 这种关联在女性和黑人中更为明显,突出了VAIAI.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 代谢健康 代谢健康
背景情况:
- 内脏脂肪指数 (VAI) 整合了BMI,性别,腰围,甘油三和高密度胆固醇,以反映身体脂肪的分布.
- 虽然VAI可以预测临床结果,但其对早逝死亡率和预期寿命的影响尚未得到充分证实.
研究的目的:
- 调查VAI与早逝死亡之间的关联.
- 为了检查VAI与美国成年人口的预期寿命之间的关系.
主要方法:
- 利用了1999-2018年国家健康和营养检查调查 (NHANES) 的数据,与国家死亡指数相关联.
- 分析了VAI四分位数 (Q1-Q4) 以及它们与过早死亡率 (80岁前死亡) 和预期寿命的相关性.
- 包括超过43,000名美国成年人,平均随访时间为9.2年.
主要成果:
- 较高的VAI四分位数 (Q3,Q4) 与较低的四分位数 (Q1) 相比,与提前死亡风险的增加有显著关联.
- 在女性和黑人参与者中,VAI和早逝率之间的关联更加明显.
- 较高的VAI与40岁预期寿命的减少有关,女性和黑人个人观察到的减少更大.
结论:
- 升高的VAI是增加过早死亡风险的重要预测因素.
- 在美国成年人中,较高的VAI与40岁的预期寿命减少有关.
- VAI对死亡率和预期寿命的影响因性别和种族/种族而异.
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