在美国成年人中,生活的简单7和外围神经病变之间的关联,一个横截面研究
Xi Gu1, Fanfan Zhu1, Ping Gao1
1Department of Endocrinology, RuiJin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Journal of health, population, and nutrition
|April 15, 2025
概括
改善心血管健康的指标Life's Simple 7 (LS7) 评分,与患上外围神经病变 (PN) 的风险降低有关. 达到最佳的LS7得分显著降低了PN的可能性.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 周围神经病变 (PN) 是成年人普遍存在的疾病,经常导致严重的健康问题.
- 生活简单7 (LS7) 是一项旨在减少心血管疾病和中风风险的指导方针.
- 在LS7坚持和PN风险之间的关系没有得到广泛的研究.
研究的目的:
- 调查遵守"生活简单7"指南与外围神经病变的患病率之间的关联.
- 确定改善心血管健康指标是否可以减轻患PN的风险.
主要方法:
- 利用了来自国家健康和营养检查调查 (NHANES) (1999-2004) 的4634名成年人 (40-85岁) 的数据.
- 使用单变量和多变量逻辑回归来分析LS7分数与PN之间的关联.
- 将LS7得分分类为不足 (0-7),平均 (8-10) 和最佳 (11-14) 进行分析,包括子组评估.
主要成果:
- 该研究包括11.59%的被诊断为PN的参与者.
- 较高的LS7得分表明与PN发病率有相反的关联.
- 在LS7得分的每一个点的增加与PN风险降低9%相关 (OR 0.91,95% CI 0.86-0.97).
- 与平均 (OR 0.75,95% CI 0.59-0.96) 和最佳 (OR 0.47,95% CI 0.28-0.79) LS7评分的参与者与不充分评分的参与者相比,PN的几率明显较低.
结论:
- 越来越多地遵守Life's Simple 7指南与降低外围神经病变的可能性显著相关.
- 在获得最佳分数的个体中,LS7对PN风险的保护作用最为明显.
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