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Updated: May 13, 2025

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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合成,抗增殖活性和分子模拟研究新型含有pyrazole-amide组的nootkatone衍生物的合成,抗增殖活性和分子模拟研究

Yin Man1,2, Guishan Lin1,2, Wengui Duan1,2

  • 1School of Chemistry and Chemical Engineering, Guangxi University, Nanning, P. R. China.

Chemistry & biodiversity
|April 16, 2025
PubMed
概括

新型的诺卡衍生型皮拉胺化合物显示出显著的抗癌潜力. 化合物4r对肝癌和乳腺癌细胞表现出强大的抗增殖活性,为药物发现提供了新的途径.

关键词:
在3D-QSAR中使用.它们具有抗增殖活性.分子对接的分子对接.没有一个Nootkatone.这是一种pyrazole-amide.

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