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Updated: May 13, 2025

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在PH-LHD中,Treg细胞通过NLRC3信号通过PH-LHD减弱肺静脉重塑

Gulinigeer Zhakeer1, Yanxi Zeng1, Guangxi E1

  • 1Department of Cardiology, Pan-Vascular Research Institute, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China (G.Z., Y.Z., G.E., N.M., P.J., Y.S., M.Z., J.Z., Q.Y., W.P.).

Circulation research
|April 16, 2025
PubMed
概括

调节性T (Treg) 细胞在左心病 (PH-LHD) 的肺高血压中防止肺静脉重塑. 在Treg细胞中NLRC3缺陷通过增加IL-18促进PH-LHD,这推动了内皮细胞到介质酶细胞的过渡.

关键词:
T淋巴细胞,调控性细胞.它们是内皮细胞的内皮细胞.高血压,肺部高血压,肺部高血压.介质蛋白-18的使用方法肺静脉 肺静脉 肺静脉

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