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Updated: May 13, 2025

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MAPK信号和 ангиопоэтин-2 促进毛细血管形的内皮透气性

Sana Nasim, Mariam Baig, Jill Wylie-Sears

    bioRxiv : the preprint server for biology
    |April 16, 2025
    PubMed
    概括

    斯特格·韦伯综合征 (SWS) 中的毛细血管形 (CM) 是由于GNAQ突变导致内皮屏障缺陷造成的. 与Trametinib一样,将ANGPT2敲击与MEK抑制相结合,有效地恢复了受影响细胞中的这种受损屏障.

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