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Updated: May 13, 2025

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

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补充C3缺乏症增强脏瘦皮球负荷和炎症,同时在慢性感染期间损害T细胞分化

Leonardo Moura Midon, Amaro Nunes Duarte Neto, Ana Maria Gonçalves da Silva

    bioRxiv : the preprint server for biology
    |April 16, 2025
    PubMed
    概括

    在感染Leptospira interrogans serovar Copenhageni (LIC) 的小鼠中缺少补充C3 (C3) 会导致脏细菌负荷增加和纤维化. C3对于T淋巴细胞的分化至关重要,它在勒螺旋症中将先天性和适应性免疫联系起来.

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