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Updated: May 13, 2025

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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Published on: July 4, 2016

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结构洞察力到凯纳特受体脱敏化中的结构洞察力

Changping Zhou, Guadalupe Segura-Covarrubias, Nami Tajima

    bioRxiv : the preprint server for biology
    |April 16, 2025
    PubMed
    概括

    凯纳酸受体 (KARs) 在脱敏过程中经历独特的结构变化,与其他离子转移性谷氨酸受体 (iGluRs) 不同. 结构和功能数据显示,KAR联体结合域旋转对于完整的通道关闭和明显的脱敏机制至关重要.

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