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化学查确定了p38 MAPK抑制作为组合性SMA治疗的候选神经保护策略

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    bioRxiv : the preprint server for biology
    |April 16, 2025
    PubMed
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    抑制p38 MAPK通过改善运动功能,在脊柱肌肉缩 (SMA) 中提供神经保护. 与SMN增强药物的联合疗法在SMA小鼠中显示出协同效益.

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