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Updated: May 13, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Published on: March 31, 2019

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CHD7与Sox11位点中的不同区域结合,以调节神经元分化

Edward Martinez, Azadeh Jadali, Jingyun Qiu

    bioRxiv : the preprint server for biology
    |April 16, 2025
    PubMed
    概括

    染色体螺旋酶DNA结合蛋白7 (CHD7) 通过调节SOX11基因中的染色质可访问性来调节神经元分化. 这种机制对神经发育至关重要,并为CHD7相关疾病,如CHARGE综合征提供了洞察力.

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