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Updated: May 13, 2025

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging
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核形态和3D成像的整合,以描述细胞社区的情况

André Forjaz, Donald Kramer, Yu Shen

    bioRxiv : the preprint server for biology
    |April 16, 2025
    PubMed
    概括

    三维 (3D) 组织学和核细分揭示了组织微环境中的关键空间模式. 这种先进的成像方法增强了对核形态和免疫细胞分布的理解,以获得疾病洞察力.

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    Electron Microscope Tomography and Single-particle Reconstruction01:07

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    Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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