使用电荷检测质谱和质光学对完整的基于mRNA的疗法进行表征

Evolène Deslignière1,2, Lauren F Barnes3, Thomas W Powers3

  • 1Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, 3584 CH Utrecht, the Netherlands.

概括

新的质谱法准确地测量了用于疫苗开发的大型mRNA分子. 电荷检测和质量光度分析完整的mRNA高达9400nT,克服了以前的分析限制.

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