在全身麻醉期间输血引起的长期过敏性循环衰竭
M Kuroki1, A Narisawa1, Y Yokoyama1
1Department of Anaesthesiology Yamagata University Hospital Yamagata Japan.
Anaesthesia reports
|April 16, 2025
概括
输血可以在麻醉期间引起严重的过敏反应,需要长时间的上腺素输注. 这一案例凸显了由于过敏原清除延迟而导致输血诱导的过敏反应需要仔细监测的需要.
科学领域:
- 麻醉学 麻醉学
- 免疫学 免疫学 免疫学
- 输血医学 输血医学
背景情况:
- 总麻醉期间的过敏反应可以由各种药物触发,包括输血.
- 虽然通常用上腺素球体进行管理,但长期的循环衰竭很罕见.
研究的目的:
- 在全身麻醉期间输血后报告长期过敏性循环衰竭病例.
- 调查可能导致和治疗严重的输血诱导过敏反应的可能原因.
主要方法:
- 一个79岁的男性接受了腹腔镜全胃切除术的案例介绍.
- 治疗包括立即输入静脉上腺素,然后进行持续输注,并排除其他常见麻醉剂作为触发剂.
- 监测胰岛素和酸酶血清度.
主要成果:
- 患者在开始输血后不久就出现了带有循环崩的过敏反应.
- 持续24小时以上的上腺素注射是必要的,因为在剂量减少后循环衰竭的复发.
- 升高的组胺和酶水平与降低的上腺素剂量相关,这意味着输血是原因.
结论:
- 输血是一般麻醉期间严重过敏反应的潜在原因.
- 输血诱导的过敏反应可能需要长时间的上腺素输注,因为过敏原的清除速度很慢.
- 警的患者监测对于管理如此复杂的病例至关重要.
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