Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.4K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.4K
Cancer Therapies02:49

Cancer Therapies

7.5K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.5K
Tumor Immunotherapy01:27

Tumor Immunotherapy

404
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
404

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Real-time sensing-integrated organoid-on-a-chip platforms: Technological progress and emerging biomedical applications.

Bioactive materials·2026
Same author

A hypoxic microfluidic organoid-on-a-chip system for studying the efficacy of metronidazole-modified nanomaterials against cholangiocarcinoma established within the chip.

Lab on a chip·2026
Same author

Advances in ultrasensitive detection technologies for blood-based biomarkers of Alzheimer's disease.

Journal of materials chemistry. B·2026
Same author

ProtoDiff: Prototypical Diffusion Model for Few-Shot Molecular Image Generation.

IEEE transactions on computational biology and bioinformatics·2025
Same author

A prognostic framework integrating endoplasmic reticulum stress dynamics reveals clinical stratification and differential prognostic attributes in osteosarcoma patients.

Frontiers in medicine·2025
Same author

Determining the optimal transplantation window in hepatic organoids via real-time biosensing of vascularization and metabolic maturation utilizing the integrated organoid-on-a-chip platform.

Biosensors & bioelectronics·2025

相关实验视频

Updated: May 13, 2025

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
09:44

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

10.0K

辐射激活的基化化化化框架用于瘤多重疗法

Qijun Du1,2, Hongwei Jiang3, Di Wu1,2,4

  • 1Clinical Research Center for Respiratory Disease, West China Hospital, Sichuan University, Chengdu 610065, China.

Biomaterials research
|April 16, 2025
PubMed
概括

这项研究引入了新的纳米粒子,通过克服瘤缺氧和增加癌细胞死亡来增强辐射动态疗法 (RDT). 新的药物输送系统显示了改善基于辐射的癌症治疗的承诺,毒性最小.

更多相关视频

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
09:01

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

3.0K
PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

9.4K

相关实验视频

Last Updated: May 13, 2025

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
09:44

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

10.0K
Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
09:01

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

3.0K
PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

9.4K

科学领域:

  • 生物医学工程 生物医学工程
  • 纳米技术纳米技术
  • 在瘤学瘤学.

背景情况:

  • 辐射动态疗法 (RDT) 对癌症治疗具有前景,但面临着诸如辐射敏感性低下和瘤缺氧等挑战.
  • 开发有效的策略来克服这些局限性对于提高R&DT效率至关重要.

研究的目的:

  • 开发一种可生物降解的新型药物输送系统,用于协作RDT和放射治疗 (RT).
  • 为了研究素和索拉芬尼布装载的ZIF67纳米颗粒 (QSZPNP) 涂有多多巴胺的潜力,克服瘤缺氧和增强RDT.

主要方法:

  • 合成的聚多巴胺涂层ZIF67纳米颗粒装有奎尔丁和索拉芬尼 (QSZPNP).
  • 评估的QSZPNP用于X射线敏感化和活性氧物种 (ROS) 在体外生成.
  • 在X射线照射下对HepG2瘤携带的小鼠模型中评估了QSZPNP的治疗疗效和全身毒性.

主要成果:

  • QSZP NPs有效控制了瘤微环境 (TME) 并克服了缺氧.
  • 试验室研究证实了纳米粒子在X射线敏感化和ROS介导作用方面的潜力.
  • 在体内研究表明,在HepG2瘤模型中,没有明显的全身毒性,具有良好的治疗效果.

结论:

  • 开发的QSZPNP为协同RDT/RT和抗血管性癌症治疗提供了有希望的方法.
  • 这种新型纳米粒子系统有效地解决瘤缺氧问题,并提高基于辐射的癌症治疗结果.