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Updated: May 13, 2025

Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software
08:22

Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software

Published on: July 17, 2018

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两种大肠杆菌l-asparaginase II变体之间的生物化学和生物物理差异:使用EcA2-K12作为生物类似物的潜力

Talita Stelling de Araujo1, Anna Catharinna da Costa1,2, Camila Dias Leite da Silva1

  • 1Protein Advanced Biochemistry (PAB), Institute of Medical Biochemistry (IBqM)-National Center for Structural Biology and Bioimaging (CENABIO), Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.

Biochemistry
|April 16, 2025
PubMed
概括

大肠杆菌l-asparaginase II (EcA2) 变种显示出不同的治疗潜力. 虽然EcA2-4M具有更高的活性,但EcA2-K12对l-asparagine具有更大的特异性,可能减少白血病治疗中的副作用.

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Analyzing DNA-Protein Interactions with Streptavidin-Based Biolayer Interferometry08:07

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Noncovalent Attractions in Biomolecules

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Evolutionary Relationships through Genome Comparisons02:54

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