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在电疗法诱导的发作中,内压升高

Jochem K H Spoor¹, Rutger V A Hollestelle², Tom K Birkenhager^3,4

¹Deptartment of Neurosurgery, Erasmus University Medical Centre Rotterdam, Rotterdam, the Netherlands.

European journal of neurology

|April 16, 2025

概括

一般性发作暂时增加视神经外直径 (ONSD),表明内压力 (ICP) 暂时上升. 这种非侵入性的ONSD测量提供了一种新的方法,用于在发作期间监测ICP.

科学领域:

神经外科神经外科
神经学神经学
麻醉学麻醉学

背景情况:

增加的内压力 (ICP) 是神经外科患者的一个关键因素,但其在发病率中的作用还未得到充分研究.
在发作期间进行非侵入性ICP监测具有挑战性,限制了人们对中ICP动态的理解.
视神经外直径 (ONSD) 是相对ICP变化的一个有希望的非侵入性标志物.

研究的目的:

调查电疗法 (ECT) 诱导的发作和ONSD变化之间的关系.
评估使用ONSD作为一般性发作期间ICP波动的非侵入性指标的可行性.

主要方法:

在9名在多个时间点接受ECT的患者中测量了ONSD:基线,在苏西尼尔胆注射期间以及在/之后的电动诱导发作.
使用线性混合模型来分析ONSD变化.
测量时间为t0 (基线),t1 (苏基尼尔胆期间),t2 (苏基尼尔胆后),t3 (发作期间) 和t4 (发作后).

主要成果:

在几乎所有发作中,从基线到发作 (t0到t3) 观察到显著的ONSD增加 (>0.2毫米).
在苏奇尼尔胆诱导的结 (t1) 和电气诱导的 (t3) 期间,ONSD显著增加.
在 (t2) 和 (t4) 之后,ONSD恢复到基线水平.

结论:

普遍性发作与ONSD的短暂,显著增加有关.
这种ONSD升高表明在发作期间内压力暂时上升.
ONSD测量提供了一种可行的非侵入性方法,用于在发作的情况下监测ICP动态.

关键词:

抑郁抑郁症抑郁症抑郁症抑郁症是一种.内压力内压力提高了ICP的价格.发作发作发作

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