1992年至2021年欧洲皮肤恶性黑色素瘤死亡率趋势
Mercedes Sendín-Martín1, Rocío Bueno Molina1, Juan-Carlos Hernández-Rodríguez1
1Department of Dermatology, Virgen del Rocío University Hospital, Seville, Spain.
Clinical and experimental dermatology
|April 16, 2025
概括
欧洲黑色素瘤死亡率趋势表现出复杂的模式,年轻人中的死亡率正在下降,但中欧/东欧和北欧男性的担忧正在增加. 年龄和性别显著影响这些趋势,需要有针对性的策略.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 皮肤黑色素瘤是一种高度侵略性的皮肤癌,发病率不断增加.
- 全球黑色素瘤死亡率趋势显示出显著的地理差异,特别是在欧洲.
研究的目的:
- 分析1992年至2021年间28个欧洲国家的黑色素瘤死亡率趋势.
- 调查性别和年龄组 (45岁以下,45-74岁,75岁以上) 对这些死亡率趋势的影响.
主要方法:
- 使用全球疾病负担数据 (1992-2021) 的纵向生态研究.
- 按年龄和性别对死亡率数据进行分层,计算年龄标准化死亡率 (ASMR).
- 加入点回归分析以确定趋势变化并分析年龄,时期和队列效应.
主要成果:
- 根据国家,性别和年龄观察到黑色素瘤死亡率的显著差异.
- 在75岁以上的患者中,ASMR增加到2015年,最近稳定或下降;自20世纪90年代以来,年轻患者显示下降率.
- 最近在中欧/东欧和北欧男性群体中发现的死亡率上升趋势.
结论:
- 黑色素瘤死亡率趋势复杂,受到年龄和性别的严重影响.
- 特定的人口统计数据,包括中欧/东欧人口和北欧男性,需要集中监测.
- 适应性公共卫生策略对于应对风险群体中黑色素瘤死亡率新出现的增加至关重要.
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