使用单一超声系统的肝硬化减弱系数:测量参数与操作员协议和诊断性能相关联的关系
Giovanna Ferraioli1, Davide Roccarina2,3, Richard G Barr4,5
1Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Campus della Salute, presso Policlinico San Matteo, Viale Golgi 19, Pavia, 27100 Italy.
AJR. American journal of roentgenology
|April 16, 2025
概括
优化超声波减弱系数 (AC) 测量用于肝脂肪量化需要标准化的协议. 这项研究确定了AC测量的最佳参数,改善了观察者间的协议和诊断性能,用于检测肝胆固醇症.
科学领域:
- 医疗成像医学成像
- 肝病学 肝病学是一种肝病学.
- 定量超声波检查是什么
背景情况:
- 超声衰减系数 (AC) 用于肝脂肪评估的临床应用受到不一致的协议和变化的限制.
- 标准化对于在临床实践中可靠采用AC测量至关重要.
研究的目的:
- 评估兴趣区域 (ROI) 深度,大小和信任地图值如何影响观测者之间的协议和超声波交流测量的诊断准确性.
- 为了将超声波交流测量与MRI质子密度脂肪分数 (PDFF) 进行比较,以检测和分类肝硬化.
主要方法:
- 对101名患有肝硬化风险或已知肝硬化风险的成年人进行前性研究.
- 两名操作员获得了超声波交流视频,独立测量了24个参数组合 (ROI深度,大小,置信值) 的交流.
- MRI PDFF 作为肝脂肪量化的参考标准.
主要成果:
- 在所有交流测量参数组合中观察到优秀的互操作协议 (ICC:0.92-0.98).
- 交流和MRI PDFF之间最强的相关性发生在ROI深度为4.0厘米时.
- 最佳的诊断性能用于稳定性的检测,在4.0厘米深度,4.0厘米大小和40%的值时得到了实现,尽管对于0级以上的稳定性的最高准确度是3.0厘米深度.
结论:
- 超声波交流测量表明,无论参数组合如何,观察者之间的一致性很高.
- 投资回报率深度为4.0厘米,与MRI PDFF产生了最强的相关性.
- 特定的参数组合提高了肝硬化检测的诊断性能,指导了协议标准化.
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