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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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相关实验视频

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Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training
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自己打印骨髓活检模拟器与人类尸体相比

Jean-Francois Leclerc1, Tristan Samson-Roy, Maxime Chénard-Poirier

  • 1From the Department of Medicine (J.-F.L., T.S.-R., M.C.-P., A.L.), Faculty of Medicine, Université Laval, Quebec City, Canada; and Faculty of Pharmacy (M.-L.T.), Université Laval, Quebec City, Canada.

Simulation in healthcare : journal of the Society for Simulation in Healthcare
|April 16, 2025
PubMed
概括

一个新的3D打印模拟器用于骨髓活检培训,产生了比尸体更高质量的标本. 这种低成本,易于使用的工具增强了居民的信心和在血液病瘤学和内科中获得程序技能.

关键词:
通过3D打印打印3D打印.骨髓活检 骨髓活检基于模拟的学习在 cadaveric 实践实践中.血液学 血液学 血液学内部医学是内科的专业.医疗模拟 医疗模拟程序技巧 程序技能 程序技巧训练模拟器训练训练模拟器

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科学领域:

  • 医学教育 医学教育
  • 生物医学工程 生物医学工程
  • 手术模拟器手术模拟器

背景情况:

  • 骨髓活检是内科和血液瘤学学员的关键技能.
  • 低于最佳的样本采集在经验较少的从业人员中很常见,导致诊断错误和重复程序.
  • 现有的培训方法,如尸体模拟和商业模拟器,面临成本和可访问性障碍,而目前的3D打印模型缺乏基本功能.

研究的目的:

  • 开发和评估一个低成本的,3D打印的程序模拟器,用于骨髓活检培训.
  • 评估模拟器的功能忠实性,易用性和在生产高质量的标本方面的有效性.
  • 为了比较新型模拟器的性能与传统的尸体实践.

主要方法:

  • 一个3D打印模拟器的设计是基于后部上部椎的解剖特征.
  • 主要设计特点包括功能忠实性,易于打印/组装,低成本和耐用性.
  • 一项随机交叉研究将3D打印模拟器与38名第一年内科住院医生的尸体实践进行了比较.

主要成果:

  • 居民在与3D打印模拟器和尸体一起练习后报告了类似的信心和欣赏水平.
  • 在10分钟内,86%的使用模拟器的居民获得了≥15毫米 (平均27毫米) 的标本,而用尸体的60% (平均17毫米).
  • 模拟器有助于获取更多和更长的标本.

结论:

  • 与尸体实践相比,3D打印模拟器使居民能够获得更高质量的骨髓活检标本.
  • 模拟器允许学员专注于通过骨皮和骨髓掌握关键的钻孔运动.
  • 这种低成本,易于组装的模拟器使生物检查培训对各种教育环境进行了民主化.