多重环境暴露与泛性焦虑症症状之间的关联在前性,美国的队列研究中
Unnati V Mehta1,2, Grete E Wilt1,2, Charlotte Roscoe1,3
1Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Environmental health perspectives
|April 16, 2025
概括
更高的邻里绿色和社会经济地位可能会保护人们免受普遍焦虑症 (GAD) 症状的影响. 相反,空气污染 (二氧化),温度和可行性与增加GAD症状有关,特别是在贫困地区.
科学领域:
- 环境健康科学 环境健康科学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 越来越多的证据将环境暴露与焦虑症状的发展和恶化联系在一起.
- 建筑和自然环境因素越来越被认为是心理健康状况的潜在贡献者.
研究的目的:
- 调查社区社会经济地位 (nSES),可行性,绿色,空气污染 (PM2.5,NO2) 和温度与普遍焦虑症 (GAD) 症状之间的关联.
- 检查这些环境暴露对GAD症状的个人和联合影响.
主要方法:
- 利用了护士健康研究II的81,897名参与者的数据,测量了2013年和2017年的GAD症状 (GAD-7).
- 使用时空模型评估环境暴露,包括nSES,可行性,绿色 (NDVI),PM2.5,NO2和住宅层面的温度.
- 采用纵向逻辑回归,GEE模型和量子g计算来分析暴露结果关系和效果修改.
主要成果:
- 单次暴露模型显示,较高的绿色和较低的GAD症状之间存在关联,而NO2,温度和可行性与增加的GAD症状有关.
- 在联合暴露模型中,nSES和绿色仍然与减少GAD症状有关;其他关联被减弱.
- 与绿色,温度和NO2的关联被nSES修改,在社会经济贫困地区观察到更强的不良影响.
结论:
- 较高的夏季绿色和nSES可能会提供对GAD症状的保护.
- 二氧化,温度和可行性与GAD症状有不良关联,特别是在弱势社区.
- 环境暴露可能对其对GAD症状的影响产生敌对的相互作用.
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