Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

The Synapse02:47

The Synapse

119.7K
Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
119.7K
Overview of Synapses01:25

Overview of Synapses

2.1K
A synapse is a specialized structure where two neurons connect, allowing them to pass an electrical or chemical signal to another neuron. It is the point of communication between neurons. The term "synapse" is derived from the Greek word "synapsis," which means "conjunction." The entire process of neural communication revolves around the synapse. When activated, a neuron releases chemicals known as neurotransmitters into the synapse. These neurotransmitters cross the...
2.1K
Synaptic Signaling01:09

Synaptic Signaling

5.4K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
5.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Unfurling the role of dysferlin's C2A domain.

The Journal of general physiology·2026
Same author

Cholesterol pools cooperate to modulate HCN channels.

The Journal of general physiology·2026
Same author

ID helps verify coincidence detection.

The Journal of general physiology·2026
Same author

Cavβ dances the two-step with VSD II.

The Journal of general physiology·2025
Same author

The origins of oscillations.

The Journal of general physiology·2025
Same author

Skeletal muscle gets some help down the stretch.

The Journal of general physiology·2025

相关实验视频

Updated: May 13, 2025

Author Spotlight: Analyzing the Synaptic Ultrastructure in Mature Retinal Organoids Using TEM
05:43

Author Spotlight: Analyzing the Synaptic Ultrastructure in Mature Retinal Organoids Using TEM

Published on: June 7, 2024

797

对棒突触的一种现实的看法

Ben Short1

  • 1Science Writer, Rockefeller University Press, New York, NY, USA.

The Journal of general physiology
|April 16, 2025
PubMed
概括

解剖学上现实的模拟显示了杆突触结构如何影响谷氨酸动力学和后突触反应. 这项研究阐明了突触架构在视觉处理中的功能作用.

科学领域:

  • 神经科学是一个神经科学.
  • 计算生物学 计算生物学
  • 细胞生物学 细胞生物学

背景情况:

  • 棒光受体对于低光下视力至关重要.
  • 在棒光受体终端的突触传输是复杂的.
  • 了解谷氨酸的动态是光受体功能的关键.

研究的目的:

  • 为了研究杆突触架构对谷氨酸酸的动态的影响.
  • 基于现实的突触结构来建模突触后反应.

主要方法:

  • 在解剖学上真实的模拟杆突触.
  • 谷氨酸释放和扩散的计算建模.
  • 对 postsynaptic受体激活的分析.

主要成果:

  • 突触结构显著塑造了谷氨酸度的短暂性.
  • 特定的结构特征与改变后突触信号相关.
  • 模拟结果提供了关于突触功效的见解.

结论:

  • 杆突触的复杂架构不仅仅是结构性的,而且具有功能意义.
  • 突触几何学在调节神经递质动态和信号传输方面发挥着至关重要的作用.

更多相关视频

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals
08:38

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals

Published on: May 25, 2011

15.5K
Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
08:08

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Published on: June 24, 2015

11.4K

相关实验视频

Last Updated: May 13, 2025

Author Spotlight: Analyzing the Synaptic Ultrastructure in Mature Retinal Organoids Using TEM
05:43

Author Spotlight: Analyzing the Synaptic Ultrastructure in Mature Retinal Organoids Using TEM

Published on: June 7, 2024

797
Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals
08:38

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals

Published on: May 25, 2011

15.5K
Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
08:08

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Published on: June 24, 2015

11.4K
  • 这些发现提升了我们对细胞水平视觉感官处理的理解.