对通用多属性实用工具的最小重要变化进行系统审查,并为其估计提出建议
Glen J Henson1, Ingrid van der Mei1, Bruce V Taylor1
1Menzies Institute for Medical Research (University of Tasmania), 17 Liverpool St, Hobart, TAS, 7000, Australia.
概括
本研究审查了多属性实用工具 (MAUI) 的最小重要变化 (MIC). 目前的MIC有报告缺陷和各种估计方法,建议谨慎使用它们用于健康经济学.
科学领域:
- 卫生经济学 卫生经济学
- 生活质量研究 研究 生命质量研究
- 心理测量 心理测量 心理测量
背景情况:
- 最少重要的变化 (MIC) 定义了临床上有意义的改善.
- 多属性实用工具 (MAUIs) 衡量与健康有关的生活质量.
- 对于MAUI MICs,没有系统审查或指导方针.
研究的目的:
- 对MAUIs的MIC进行系统审查.
- 制定用于估计MAUI MICs的准则.
- 解决MAUI MIC研究中的证据缺口.
主要方法:
- 系统搜索十个数据库.
- 提取数据的叙述和描述性分析.
- 评估报告质量 (准确性,敏感性,有效性).
主要成果:
- 从68项研究中确定了282个独特的基MIC.
- EQ-5D-3L,EQ-5D-5L和SF-6D.v1是最常见的MAUIs. 这是最常见的MAUIs.
- 平均变化得分是最常用的估计方法;报告质量不足.
结论:
- 现有的MAUI MIC文献存在报告和方法方面的问题.
- 研究人员应谨慎使用当前的MAUI MIC.
- 建议的建议可以帮助未来在健康经济学中评估MIC.
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