结构学习算法的社会流行病学中的贡献:应用于现实世界的数据
Helene Colineaux1, Benoit Lepage1,2, Pierre Chauvin3
1EQUITY Team, Centre d'Epidémiologie et de Recherche en Santé des POPulations (CERPOP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Toulouse III University, 37 Allées Jules Guesde, 31062 Toulouse, France.
概括
结构学习 (SL) 方法可以通过揭示变量关系来帮助社会流行病学研究. 然而,纯粹基于数据的方法可能会错过关联和误导关系,需要先前知识的验证.
科学领域:
- 社会流行病学 社会流行病学
- 数据分析 数据分析
- 网络分析 网络分析
背景情况:
- 流行病学家分析复杂,大型数据集,使用越来越多的分析技术,如机器学习.
- 在观察性研究中,了解变量关系,因果关系和网络结构至关重要.
研究的目的:
- 评估结构学习 (SL) 方法在社会流行病学中的贡献和局限性.
- 探索SL在确定医疗保健系统访问的决定因素中的应用.
主要方法:
- 在巴黎的2010年SIRS队列数据 (N=3006) 上应用了SL技术.
- 与非自动化流行病学方法 (专家网络,物流回归) 进行了自动化SL算法 (有/没有约束) 的比较.
- 分析了医疗保健利用率作为结果,其中的决定因素包括健康状况,人口统计和社会经济因素.
主要成果:
- 两种方法都确定了变量之间的相似相互依赖性和相对强度.
- 与非自动化方法相比,SL算法检测到与结果的关联较少.
- 纯粹数据驱动的SL方法有时会产生错误的定向关系.
结论:
- 在社会流行病学中,SL方法对探索性分析和假设生成有价值.
- 数据驱动SL的结果需要根据现有知识进行验证,并进行进一步的确认分析.
- SL可以协助挖掘新型数据库,以发现复杂的变量相互作用.
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