李斯特菌单细胞菌和李斯特菌病:全球难解之
Christy E Manyi-Loh1, Ryk Lues1
1Centre for Applied Food Sustainability and Biotechnology, Central University of Technology, Bloemfontein X9301, South Africa.
Foods (Basel, Switzerland)
|April 16, 2025
概括
李斯特菌单细胞菌是一种危险的食源性病原体,导致致命的李斯特菌病爆发. 这项研究回顾了其特征,抗生素耐药性和对准备食用的食品的控制.
科学领域:
- 食品安全 食品安全
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 李斯特菌单细胞菌是一种由食物传播的精神变性病原体,是导致李斯特菌病的病原体,这种感染的死亡率很高.
- 像南非致命的疫情这样的疫情凸显了这种细菌对公共卫生构成的重大威胁.
- 它在恶劣环境中形成生物膜和发展抗生素耐药性的能力,对即食食品行业构成了挑战.
研究的目的:
- 提供对Listeria monocytogenes的最新审查,涵盖其特征,流行病学和抗生素耐药性.
- 巩固当前对病原体的知识,以改善理解和控制策略.
- 突出监测Listeria monocytogenes中抗生素耐药性趋势的重要性.
主要方法:
- 在各种数据库和搜索引擎中进行了全面的文献搜索.
- 收集信息并按时间顺序排列,重点关注Listeria monocytogenes和李斯特菌病.
- 分析了来自不同来源的抗生素耐药性概况数据,以确定趋势.
主要成果:
- 这项研究综合了关于Listeria monocytogenes的最新信息,提高了对病原体的理解.
- 从食物,人类和环境来源的菌株中注意到抗生素耐药性增加,特别是关键治疗药物.
- 监测显示了抗生素耐药性概况的变化,表明了不断变化的趋势.
结论:
- 了解Listeria monocytogenes及其传播对于预防和控制食源性疾病至关重要.
- 持续监测抗生素耐药性对于调整控制策略至关重要.
- 有效监测细菌污染是确保食品工业食品安全的关键.
相关概念视频
Colonisation of Pathogens
Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
Investigation of Disease Outbreaks
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Toxoplasmosis
Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Encephalitis ll: Pathophysiology
Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...


