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Updated: Jul 2, 2026

High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity
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对抗微生物化合物诱导的细菌细胞细胞死亡单细胞分析

Md Zahidul Islam1,2, Farzana Hossain1,3, Masahito Yamazaki1,4,5

  • 1Nanomaterials Research Division, Research Institute of Electronics, Shizuoka University, Shizuoka 422-8529, Japan.

The Journal of antimicrobial chemotherapy
|April 16, 2025
PubMed
概括

单细胞分析揭示了抗菌化合物 (AMC) 如抗生素和抗菌 (AMP) 如何杀死细菌. 这种方法追踪了膜损伤和细胞死亡,为未来药物开发提供了AMC机制的见解.

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Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...