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从原子模拟中转移人类线粒体RNA聚合酶 (POLRMT) 时的集体变量和促进的 conformational 开放

Shannon J McElhenney1, Jin Yu1,2

  • 1Department of Chemistry, University of California-Irvine, Irvine, California 92697, United States.

Journal of chemical theory and computation
|April 16, 2025
PubMed
概括

人类线粒体RNA聚合酶 (POLRMT) 转位与核酸结合相结合,使得转录的必要指纹子域开放. 这一过程发生在几百微秒的时间内,表明布朗的拉切特机制对基因表达的调节.

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