移动应用程序在改善慢性病患者药物服药的有效性:系统性审查
Ganesh Sritheran Paneerselvam1,2, Pei Lin Lua3, Wen Han Chooi4
1School of Pharmacy, Taylor's University, Subang Jaya, Malaysia.
Journal of medical Internet research
|April 16, 2025
概括
移动应用程序可以改善慢性病 (CKD) 患者的药物坚持. 然而,有限的证据和短期的研究要求进一步研究最佳的应用程序功能和成本效益.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 数字健康数字健康
- 医疗信息学 医疗信息学
背景情况:
- 慢性病 (CKD) 影响全球数以百万计的人,而低于最佳的药物坚持导致了糟糕的结果.
- 移动应用程序越来越多地被认为具有提高慢性疾病中药物坚持和自我管理的潜力.
研究的目的:
- 系统地审查移动应用程序在改善慢性病 (CKD) 患者,包括末期病患者和替代疗法患者的药物坚持方面的有效性.
主要方法:
- 在主要数据库 (Scopus,Cochrane,PubMed,EBSCOhost) 进行了系统的文献搜索.
- 使用纽卡斯尔-太华尺度和柯克兰偏差风险工具来评估研究质量.
- 九项符合条件的研究,主要是随机对照试验,被纳入了审查.
主要成果:
- 在九个移动应用程序中,有五个显示出对药物坚持的统计学上显著的积极影响 (P<.05).
- 有效的策略包括提醒,游戏化,患者教育和电子药物监测.
- 强有力的证据支持了结合游戏化,提醒,电子监控和教育的干预措施.
结论:
- 移动应用程序在改善CKD患者的药物坚持方面表现有前途.
- 证据水平低,干预时间短,需要谨慎解释.
- 未来的研究应该专注于确定理想的应用程序功能,成本效益以及用户友好和安全的应用程序.
相关概念视频
01:17Factors Affecting Renal Clearance: Renal Impairment
35
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
35
01:22Heart Failure Drugs: Diuretics
294
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
294
01:33Hormonal Regulation
32.7K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
32.7K
01:11Renal Failure: Dose Adjustments
37
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
37
01:28Drug Therapy
30
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
30
01:27Dialysis
231
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
231