种子和土壤启发的水凝微球:一种双重作用的抗氧化剂和细胞疗法,用于逆转椎间盘退化

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A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
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A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.

Published on: February 14, 2021

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Yilin Yang1, Jiangbo Guo1, Haifei Cao2

  • 1Department of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedics Institute, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College, Soochow University, Suzhou, 215000, China.

Biomaterials
|April 16, 2025
PubMed
概括

这项研究开发了装有核细胞 (NPC) 的抗氧化水凝微球,用于治疗椎间盘退化症 (IVDD). 微球修复组织,并通过清除活性氧物种 (ROS) 和恢复细胞外基质 (ECM) 来发挥作用.

关键词:
双重作用的抗氧化剂抗氧化剂细胞外矩阵是细胞外矩阵.水凝微球是一种微球.椎间盘退化 椎间盘退化种子和土壤战略

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