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Updated: May 13, 2025

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来自微生物的胆汁酸对抗宿主雌激素受体并驱动抗瘤免疫力

Wen-Bing Jin1, Leyi Xiao2, Mingeum Jeong2

  • 1Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA; Gastroenterology and Hepatology Division, Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, Cornell University, New York, NY, USA; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China.

Cell
|April 16, 2025
PubMed
概括

来自微生物群的胆汁酸 (BAs) 影响宿主健康. 研究人员发现了抗人类雌激素受体 (hAR),影响基因表达,为癌症提供新的治疗途径.

关键词:
受体受体抗瘤免疫力胆酸的HSDHs胆酸新陈代谢肠道微生物群主体与微生物的相互作用微生物生物的胆酸

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