科洛斯:使用大数据进行辐射流行病学研究的软件
Eric Giunta1, Dawson Stutzman1, Sarah S Cohen2
1Kansas State University, Manhattan, KS, United States of America.
概括
科洛斯是一个新的R包,用于对大型辐射流行病学数据集进行可扩展的生存分析. 它准确地分析数百万行,与现有软件和已发布的结果对其性能进行验证.
科学领域:
- 流行病学 流行病学
- 生物统计学 生物统计学
- 辐射科学 辐射科学
背景情况:
- 对于大规模辐射流行病学数据的生存分析软件的需求越来越大.
- 在处理数百万行数据时,现有的软件限制.
研究的目的:
- 介绍Colossus,一个R包用于可扩展的生存分析.
- 提供总和相对速率方程,用于回归模型.
- 根据现有的软件和已发表的结果验证Colossus的性能.
主要方法:
- 开发了Colossus R软件包的开发工作.
- 实现总和相对利率方程.
- 考克斯比例危险,波桑和细灰回归模型的应用.
- 与现有软件 (Epicure) 和已发表的数据进行比较分析.
主要成果:
- 科洛斯成功分析了大量的辐射流行病学数据集 (数百万行).
- 使用Colossus获得的结果与现有软件一致.
- 验证证实了与以前的出版物相比,Colossus的准确性.
结论:
- 科洛斯在辐射流行病学中为生存分析提供了可扩展和准确的解决方案.
- R包适用于分析大型数据集,例如百万人研究的数据集.
- 科洛斯的性能得到了验证,并与已确定的方法可比.
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