辐射疗法治疗的进步 精准医学的工作流程:一篇回顾和展望未来
Yi Rong1, Riley Tegtmeier2, Edward L Clouser1
1Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona.
概括
放射治疗 (RT) 工作流程现在可以省略计划计算机断层扫描 (CT) 扫描. 新的成像技术使得有效和准确的治疗提供,改善患者的结果.
科学领域:
- 医学物理 医学物理
- 辐射瘤学 辐射瘤学
- 放射治疗技术 放射治疗技术
背景情况:
- 标准的放射治疗 (RT) 工作流程,建立了超过30年,涉及计算机断层扫描 (CT) 模拟,规划,质量保证和交付.
- 准确的3D规划和RT中的患者定位传统上取决于规划CT扫描.
研究的目的:
- 审查模拟遗漏的RT工作流程.
- 评估这些创新工作流程的程序,剂量测量效益,人员需求,计费问题和局限性.
主要方法:
- 综述现有关于先进成像技术 (如圆光束CT,MRI) 的文献.
- 分析工作流程,整合诊断CT和每日车载成像,绕过CT规划的需要.
- 对合成CT生成和图像变形等技术的评估.
主要成果:
- 先进的车载3D成像提高了剂量计的准确性,并使诸如边际减少和剂量升级等技术成为可能.
- 模拟遗漏的RT工作流程证明了可行性,效率和处理精度.
- 新的成像和适应性策略的整合提供了重要的临床创新.
结论:
- 通过现代成像技术的进步,在RT工作流程中省略计划CT扫描是可行的.
- 这些先进的工作流程有可能改进RT程序并提高患者的治疗结果.
- 影像技术和适应性策略的融合为辐射瘤学的创新提供了关键机会.
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