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Updated: May 13, 2025

Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology
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Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology

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识别转化后修改的MHC I类相关类作为潜在的癌症免疫治疗标

Keira E Mahoney1, Larry Reser2, Maria Virginia Ruiz Cuevas3

  • 1Department of Chemistry, Yale University, New Haven, CT, USA; Department of Chemistry, University of Virginia, Charlottesville, VA, USA.

Molecular & cellular proteomics : MCP
|April 16, 2025
PubMed
概括

亨特实验室确定了超过2450个与MHC分子结合的修饰,包括新型. 这些发现通过揭示T细胞识别的潜在点,推进了癌症免疫疗法.

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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

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