系统性自身免疫性风湿性疾病中的支气管疾病
Yanisa Kluanwan1,2, Nichthida Tangnuntachai3, Jay H Ryu2
1Division of Pulmonary and Critical Care Medicine, Central Chest Institute of Thailand, Nonthaburi, Thailand.
概括
小型呼吸道疾病 (SAD) 在全身性自身免疫性类风湿性疾病 (SARD) 中很常见,有时会成为主要问题. 本综述详细介绍了各种SARD的发病率,症状和治疗方法.
科学领域:
- 风湿病学和肺病学 风湿病学和肺病学
- 系统性自身免疫性风湿性疾病 (SARDs)
- 支气管疾病 (BDs) / 小气道疾病 (SAD)
背景情况:
- 肺部干扰是SARDs的一个显著并发症,影响呼吸道,肺膜,肺和呼吸机制.
- 支气管疾病 (BDs),也称为小呼吸道疾病 (SAD),是SARD患者常见的表现,可以是主要的临床特征.
研究的目的:
- 对与系统性自身免疫性类风湿性疾病 (SARDs) 相关的支气管疾病 (BDs) 进行全面的文献审查.
- 总结关于SARDs中BD的发病率,临床特征,病变发生,诊断方法和治疗策略的当前知识.
主要方法:
- 进行了系统的文献搜索,使用关键词如"支气管炎"",小呼吸道疾病"和特定的SARD名称.
- 1977年1月至2024年4月期间发表的文章被整理和审查.
- 审查的重点是总结与发病率,临床表现,病原遗传机制,肺功能测试,成像,病原学和治疗相关的数据.
主要成果:
- 支气管疾病 (BDs) 是一种常见的肺部并发症,涉及多种SARDs.
- 该综述强调了Sjögren综合征,类风湿性关节炎,全身性硬化症,全身性红斑狼,异常性炎症性肌肉炎,混合结缔组织疾病和结性脊髓炎的BD.
- 对于每个相关的SARD,讨论了包括患病率,临床表现,潜在机制,诊断结果和治疗结果在内的关键方面.
结论:
- 支气管疾病代表了系统性自身免疫性类风湿性疾病的显著且经常被忽视的肺部表现.
- 了解不同SARD中BD的特定特征对于准确诊断和有效管理至关重要.
- 需要进一步的研究来阐明病原遗传机制,并优化这些疾病的治疗策略.
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