Xerostomia 与灼热口腔综合征患者的疼痛敏感性相关
Hongsen Zhao1, Shujun Ran2, Wenqian Huo3
1Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou City, 450052, China. zhaohongsen205@163.com.
Scientific reports
|April 16, 2025
概括
燃烧口腔综合征 (BMS) 患者的 Xerostomia (口腔干燥) 与自我报告的疼痛敏感性增加有关,而不是改变身体疼痛值. 口腔干燥的持续时间与BMS中较高的疼痛分数相关.
科学领域:
- 口腔医学是指口腔医学.
- 疼痛研究 疼痛研究
- 感官科学 感官科学
背景情况:
- 燃烧口腔综合征 (BMS) 的特点是体感功能异常.
- Xerostomia (口腔干燥) 是BMS患者经常出现的并发症.
- 在BMS中,异口症与疼痛敏感性之间的关系需要进一步研究.
研究的目的:
- 在被诊断患有BMS的女性患者中,研究异口症和疼痛敏感性之间的关联.
- 为了区分异构对客观疼痛值的影响与主观疼痛感知.
主要方法:
- 招募了82名女性BMS患者,其中55人报告了异口症.
- 定量感官测试包括使用数字压力算法仪的压力疼痛值 (PPT).
- 使用疼痛敏感性问卷 (PSQ) 评估疼痛敏感性,并测量唾液流速.
主要成果:
- 在BMS患者之间没有观察到PPT或刺激的唾液流速的显著差异,无论是有或没有异口症.
- 患有异口症的BMS患者表现出显著更高的PSQ-小得分,表明自我报告的疼痛敏感性增加.
- 微小的PSQ分数与异口症的持续时间相关,但不是其严重程度.
结论:
- 在BMS患者中, Xerostomia与主观疼痛敏感度增加有关 (PSQ-小得分).
- 在这个队列中,客观的疼痛测量,如PPT,并没有受到异口症的显著影响.
- 异口症的持续时间,而不是严重程度,似乎影响了BMS的疼痛感知.
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