空气污染是早期更年期的危险因素吗?
Joyce Mary Kim1,2,3, Surabhi Shah2,3, Jieun Min1,2
1Graduate Program in System Health Science and Engineering, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.
BMC public health
|April 16, 2025
概括
暴露于空气污染,特别是细颗粒物 (PM2.5) 和PM10,与女性更年期更早发生有关. 这凸显了改善空气质量的必要性,以保护生殖健康.
科学领域:
- 环境健康 环境健康
- 生殖流行病学 生殖流行病学
- 公共卫生 公共卫生
背景情况:
- 环境空气污染构成了重大的公共卫生挑战,对妇女的生殖健康产生潜在影响,包括生育能力和更年期的时间.
- 了解早期更年期风险因素对于告知妇女健康风险和指导公共卫生战略至关重要.
研究的目的:
- 调查暴露于环境空气污染和女性更年期开始之间的关联.
- 为了确定可能影响更年期的时间的特定空气污染物.
主要方法:
- 利用了2010-2020年韩国国家健康和营养检查调查 (KHANES) 的数据.
- 连接KHANES数据与AiMS-CREATE (2002-2020) 对226个韩国地区的月平均空气污染预测.
- 分析了8506名经历过更年期的女性的数据,采用调查逻辑回归,调整共变量.
主要成果:
- 在暴露于颗粒物2.5 (PM2.5) 和早期更年期发作之间发现了显著的关联 (aOR:1.26,95% CI:1.21-1.31).
- 暴露于颗粒物10 (PM10) 也与早期更年期的风险增加有关 (aOR:1.17,95% CI:1.14-1.20).
结论:
- 调查结果表明,环境空气污染有助于更年期的开始,强调空气质量作为公共卫生优先事项.
- 需要进一步的研究来阐明与早期更年期相关的环境暴露的机制和长期健康后果.
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