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Updated: May 11, 2025

A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties
08:40

A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties

Published on: August 7, 2020

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由 YAP1 激活的 CAF 升高癌症基因硬度,以调节肝细胞癌的进展

Wei Yan1, Guo-Hui Xiao2, Li-Juan Wang1

  • 1Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, P. R. China.

Journal of translational medicine
|April 16, 2025
PubMed
概括

与癌症相关的纤维细胞 (CAFs) 驱动肝癌矩阵刚性. 一个YAP1阳性的CAF子集调高了性基因,促进了瘤的进展,并影响了HCC患者的预后.

关键词:
一个YAP1一个YAP1与癌症相关的纤维细胞.肝细胞癌是肝细胞癌.矩阵的刚度 矩阵的刚度单细胞测序是一种单细胞测序.

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