在钢铁工人中,职业危险暴露与异常骨矿物质密度之间的相关性
Haoruo Zhang1, Ziwei Zheng1, Nan Wang1
1School of Public Health, North China University of Science and Technology, No. 21 Bohai Avenue, Caofeidian New Town, Tangshan, Hebei, 063210, People's Republic of China.
BMC public health
|April 16, 2025
概括
夜班工作,高温和尘埃暴露等职业危险与钢铁工人的异常骨矿物质密度 (BMD) 有关. 组合风险显著增加了风险,突出了需要共同暴露模型来准确评估这些风险.
科学领域:
- 职业健康 职业健康 职业健康
- 骨的新陈代谢 骨的新陈代谢
- 环境流行病学环境流行病学
背景情况:
- 钢铁工人面临着许多职业危险,包括夜班工作,高温,灰尘和噪音.
- 骨矿物质密度 (BMD) 对骨健康至关重要,其异常会导致骨质疏松症等疾病.
- 在这个人群中,多种职业危险对骨损伤的综合影响仍然不完全理解.
研究的目的:
- 调查单一和综合职业危险与钢铁工人的异常骨形状之间的关联.
- 分析夜班工作,高温,尘埃和噪音暴露以及异常的骨.
- 评估单一风险评分模型 (SRSM) 和混合风险评分模型 (HRSM) 在评估共同暴露风险中的有用性.
主要方法:
- 一项涉及北京-天津-河北地区6816名钢铁工人的横截面研究.
- 评估职业危险:夜班工作,高温,尘埃和噪音暴露,单独分析和组合分析.
- 使用健康风险因子得分和部分回归系数开发和应用SRSM和HRSM.
主要成果:
- 在钢铁工人中,异常骨质瘤的患病率为27.6%.
- 在夜班工作,高温,尘埃暴露和异常的骨质量 (ORs从1.17到1.55) 之间发现了显著的关联.
- 无论是SRSM还是HRSM,都表明 BMD异常风险的剂量依赖性增加,累计暴露得分更高,OR高达2.11 (SRSM) 和2.08 (HRSM).
结论:
- 夜班工作,高温和尘埃暴露是导致钢铁工人骨质量异常的潜在因素.
- 异常骨质瘤的风险增加与职业危险共同暴露的累积风险得分较高有关.
- 同时暴露模型 (SRSM和HRSM) 提供了更准确的评估职业危险和异常的骨肌肉之间的关系.
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