药物错误的风险管理:提高药物治疗实践的质量
Richard Anthony Despott1, Patricia Vella Bonanno1,2, Charmaine Gauci1
1Department for Health Regulation, St Luke's Hospital, Pietà, Malta.
Pharmacology research & perspectives
|April 17, 2025
概括
本研究引入了质量风险管理框架,以减少医疗保健中的药物错误. 它将处方和管理错误确定为高风险,并提出针对性干预措施,以改善药物治疗实践和患者安全.
科学领域:
- 改善医疗保健质量 改善医疗保健质量
- 药物治疗 药物治疗
- 药物安全 药物安全
背景情况:
- 准确的设计规范对于评估临床性能和优先考虑医疗保健质量改善至关重要.
- 现有的框架可能无法充分解决药物治疗实践的复杂性.
- 基于证据的方法提供了一种更有效的方法来提高药物治疗中的护理质量.
研究的目的:
- 探索基于证据的方法,为药物治疗实践的质量改进框架.
- 适应利益相关者管理矩阵来定义护理质量维度和医疗保健实践规范.
- 评估预防药物错误的策略及其对患者危害的影响.
主要方法:
- 在EudraVigilance数据库中审查了可预防的药物错误导致的与药物有关的问题 (DRP).
- 分析了药物不良反应 (ADR) 的个案,以确定根本原因药物错误 (RCME).
- 根据DRP对患者伤害的频率和严重程度,评估了预防策略的影响.
主要成果:
- 从1750种药物错误中确定了1300种可预防的DRP:41%的处方,20%的发放,39%的管理错误.
- 处方错误和药物管理错误显示了最高的风险得分.
- 使用质量风险管理方法来评估干预措施在减少药物错误方面的有效性.
结论:
- 开发的理论模型为医疗保健中的战略质量领域提供了基础,并比较了药物治疗改进策略.
- 关键干预措施包括药物审查,单位剂量分配,线上质量控制和患者教育.
- 该框架在医疗保健机构中广泛适用,以分享最佳实践并减少治疗结果差异.
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