帕金森病中的突触相关研究:一个探索的趋势分析分析
Yan-Jun Chen1,2, Ming-Rong Xie3, Sheng-Qiang Zhou2
1Graduate School of Hunan University of Chinese Medicine, Changsha, China.
Frontiers in aging neuroscience
|April 17, 2025
概括
帕金森病的研究显示了日益增长的趋势,专注于α-synuclein和突触可塑性. 未来的研究可能会探索神经炎症在帕金森病进展中的作用.
科学领域:
- 神经科学是一个神经科学.
- 生物医学研究生物医学研究
- 图书统计学 图书统计学
背景情况:
- 帕金森病 (PD) 的特征是Lewy体 (聚合的α-synuclein) 和神经退行.
- 突触功能障碍是PD进展的一个关键因素.
- 了解PD和突触研究趋势至关重要.
研究的目的:
- 分析帕金森病和突触的研究热点和趋势.
- 确定前沿研究领域和未来方向.
- 绘制PD和突触功能障碍的全球研究格局.
主要方法:
- 从2001年到2024年,对3823篇出版物的图书统计分析.
- 利用Web of Science数据库进行数据采集.
- 雇佣了CiteSpace,VOSviewer和文献计量器用于可视化和分析.
主要成果:
- 从2001年到2024年,PD和突触研究的显著增长趋势.
- 美国,中国和意大利是主要的研究贡献者.
- 关键的研究领域包括α-synuclein,突触可塑性和神经炎症.
结论:
- 国际合作推动了PD研究的进步.
- 目前的研究重点是α-synuclein,突触可塑性和小鼠模型.
- 神经炎症被认为是有前途的未来研究方向.
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