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Updated: May 11, 2025

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
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Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs

Published on: July 27, 2022

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普罗波:当前的更新,挑战和策略,以改善自我纳米乳化配方.

Mohsin Kazi1,2, Ali Gaskari3, Ahmad A Shahba2

  • 1Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

ACS pharmacology & translational science
|April 17, 2025
PubMed
概括

自行纳米乳化药物输送系统 (SNEDDS) 显示出改善醇的潜力.

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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