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Updated: Jul 14, 2026

Transcriptomic Analysis of Human Retinal Surgical Specimens Using jouRNAl
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多模式神经成像变化和宿主遗传关联在患有风湿性视网膜脱落的患者:一个转录基因神经成像研究

Yu Ji1, Yi-Chong Duan, Lin Zhou

  • 1Department of Ophthalmology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China.

Neuroreport
|April 17, 2025
PubMed
概括

风湿性视网膜脱落 (RRD) 影响大脑灰质,影响视觉和认知功能. 基因分析揭示了与这些大脑变化相关的特定基因表达模式,提供了新的治疗见解.

关键词:
艾伦人类大脑图谱 艾伦人类大脑图谱基因表达的基因表达方式灰色物质是一种灰色物质.多模式成像技术多模式成像技术风湿性视网膜脱落症 视网膜脱落症

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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