系统审查患有埃索诺菲尔食道炎的儿童的食困难:EAACI工作组的报告
Maria Ruano-Zaragoza1,2, Sarah-Anne Hill3, Ulugbek Nurmatov4
1Allergy Department, Hospital Clínic Barcelona, Barcelona, Spain.
概括
食困难 (FD) 常见于患有异性食道炎 (EoE) 的儿童中,范围为13%至75.3%. 这种患病率在食物过敏的儿童中更高,但诊断不一致性限制了明确的结论.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 过敏和免疫学 过敏和免疫学
- 临床营养学 临床营养学
背景情况:
- 食困难 (FD) 是影响儿童的各种饮食问题.
- 生性食道炎 (EoE) 是一种慢性免疫疾病,影响食道,可能导致食问题.
- 在患有EoE的儿童中,FD的患病率和影响尚不清楚.
研究的目的:
- 系统地审查和确定患有乙性食道炎的儿童食困难的患病率和影响.
- 解决关于EdE与养挑战之间的关系的知识差距.
主要方法:
- 对八个国际数据库进行了系统审查,搜索到2024年3月之前发表的研究.
- 符合条件的研究进行了选,进行了批判性评估,并且由于异质性,数据进行了叙事合成.
- 十项研究符合纳入标准,分析了关于飞行器疾病患病率的定量数据.
主要成果:
- 在患有EdE的儿童中报告了食困难,患病率从13%到75.3%不等.
- 观察到高比例的同时发生的IgE食物敏感性/食物过敏 (26.2%-88%),尽管其对FD的直接影响尚不清楚.
- 在研究中,在FD的术语 (18个术语) 和诊断工具 (6个工具) 中发现了显著的异质性.
结论:
- 食困难在患有埃索诺菲尔性食道炎的儿童中普遍存在,特别是那些同时出现IgE介导的食物过敏的儿童.
- 对于FD的诊断方法和术语的广泛变化使得最终的结论变得复杂.
- 进一步的研究和标准化的诊断/管理指南对于有效识别和治疗儿科EOE患者的FD至关重要.
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