头癌切除后肺栓塞的危险因素:一项回顾性病例控制研究
Xuan Liang1, Guyan Wang1, Jing Zhou2
1Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
The Laryngoscope
|April 17, 2025
概括
头癌患者的术后肺栓塞 (PE) 与手术内低血压,寡尿和双侧部剖析有关. 监测这些因素可以帮助预测和管理手术后的PE风险.
科学领域:
- 在瘤学瘤学.
- 血管外科 血管外科
- 关键护理医学 关键护理医学
背景情况:
- 肺栓塞 (PE) 是头恶性瘤的彻底切除后的一种严重并发症.
- 确定PE的预测因素对于患者管理和风险分层至关重要.
研究的目的:
- 为了调查与手术后PE风险增加相关的临床因素,在为头部和部恶性瘤进行彻底切除的患者中.
- 确定PE的预测因子,以实现更好的风险评估和预防策略.
主要方法:
- 进行了一项追溯病例控制研究,涉及5042名在2013年至2022年期间为头恶性瘤进行了彻底切除的患者.
- 没有手术后PE的对照组在1比3的比例上匹配. 经手术后的临床数据,包括血液动力学管理,使用单变量分析和条件后勤回归进行了分析.
主要成果:
- 发育不良的发病率为0.75%. 确定的显著预测因素是平均血压 (MBP) 降低的累积时间>20% (OR=3.167),寡尿症 (OR=44.055) 和双边部剖析 (OR=3.291).
- 使用累积低血压负担预测PE的曲线下的面积 (AUC) 为0.809,值为1.17小时.
结论:
- 术内低血压,寡尿和双侧部剖析是头癌患者术后PE的显著预测因素.
- 这些发现强调了监测手术内血液动力学状态和尿液输出的重要性,以有效控制PE风险.
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