维生素B和结直肠癌:从图书识别和视觉分析 (1994-2024) 中探索研究热点和前沿
Meichen Li1, Lingshi Meng2, Hong Gu1
1Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China.
Carcinogenesis
|April 17, 2025
概括
维生素B在降低结肠直肠癌 (CRC) 风险方面表现有前途. 研究强调纳米颗粒药物输送是治疗和预防CRC的关键未来趋势.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 生物技术是生物技术.
背景情况:
- 越来越多的证据表明,B族维生素可能会降低结肠直肠癌 (CRC) 风险.
- 这一领域的研究已经显著扩大,需要全面的概述.
研究的目的:
- 分析和绘制B族维生素和结直肠癌的研究格局.
- 确定该领域的关键贡献者,机构和出版物.
- 突出目前的研究热点和CRC预防和治疗的未来趋势.
主要方法:
- 使用CiteSpace和VOSviewer对2617篇文章进行了文献计量分析.
- 关键词和引文分析以确定研究主题.
- 爆发检测分析以确定新出现的趋势.
主要成果:
- 美国和哈佛大学分别是最富有生产力的国家和机构.
- 爱德华L.Giovannucci是最常被引用的作者,癌症流行病学生物标志物和预防是主要的期刊.
- 关键的研究领域包括B族维生素机制 (基因表达,抗炎,抗氧化,肠道微环境) 用于CRC预防/治疗.
- 基于纳米粒子的向药物递送系统,特别是叶酸结合的纳米载体,是当前的热点和未来的趋势.
结论:
- 维生素B在结直肠癌研究中起着重要作用.
- 基于纳米粒子的向药物递送代表了CRC治疗未来有前途的方向.
- 这种文献计量分析为未来该领域的研究提供了宝贵的见解.
相关概念视频
Cancer Prevention
6.0K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.0K
Targeted Cancer Therapies
7.4K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.4K
Cancer Therapies
7.4K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.4K
Serum Laboratory Studies, Stool Test, Breath Test
244
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
244
Rous Sarcoma Virus (RSV) and Cancer
4.9K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
4.9K
Combination Therapies and Personalized Medicine
4.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.8K


