根据经合组织测试指南421/42222测试的有机化合物的发育和生殖毒性进行阅读交叉驱动的二元分类

M Chatterjee1, S Pore1, Z Szepesi2

  • 1Department of Pharmaceutical Technology, Drug Theoretics and Cheminformatics Laboratory, Jadavpur University, Kolkata, India.

概括

这项研究使用了 in silico 方法,特别是 Read-Across,来预测工业化学品的发育和生殖毒性 (DART). 该方法在分类新化学品方面表现出很好的准确性,为动物试验提供了替代方案.

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