改善牙医抗生素使用的干预措施:系统审查和元分析
Julieta Mendez-Romero1,2,3, Almudena Rodríguez-Fernández3,4,5, Marta Ferreira2
1Universidad Nacional de Caaguazú, Coronel Oviedo, Paraguay.
The Journal of antimicrobial chemotherapy
|April 17, 2025
概括
干预措施显著减少了70%的牙医不适当的抗生素处方. 基于审计的策略,包括反和教育,是最有效的,显示牙医对改善抗生素处方实践的接受.
科学领域:
- 牙科公共卫生 牙科公共卫生
- 传染病控制和控制传染病
- 药理学 药理学是指药理学的学科.
背景情况:
- 牙医不适当的抗生素处方有助于抗菌素耐药性.
- 需要有效的策略来优化牙科实践中的抗生素使用.
研究的目的:
- 分析旨在减少牙医不适当处方抗生素的干预措施的有效性.
- 为改善临床实践和打击牙科抗菌素耐药性的策略提供概述.
主要方法:
- 在2023年之前发表的23项研究的系统数据综合和元分析.
- 电子数据库搜索,包括MEDLINE,SCOPUS,EMBASE,COCHRANE CENTRAL,LILACS和BBO. 这些数据库的搜索方法包括:
- 包括的研究包括三项随机对照试验和20项前后研究,主要来自英国.
主要成果:
- 干预措施导致牙医中不适当的抗生素处方总体减少了70%.
- 基于审计的干预措施,特别是反 (75%) 和教育 (73.3%),显示出最大的效果.
- 随机对照试验显示63.9%的减少,而前后研究表明71%的减少,尽管证据质量较低.
结论:
- 牙医对旨在改善抗生素处方的干预措施持开放态度.
- 通过有针对性的策略,可以显著减少不适当的抗生素处方.
- 需要使用更高质量的研究设计进行进一步的研究来证实这些发现.
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