关于不同含量丰富酵母对肠道微生物群和代谢物的影响的比较研究
Zijian Zhang1, Li Zhu1,2, Hongtao Zhang1
1Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.
International journal of molecular sciences
|April 17, 2025
概括
富含的酵母,富含甲 (SeM),在模拟消化中对肠道微生物群组成和短链脂肪酸生产产生积极影响. 这表明与标准酵母或补充剂相比,对人类健康有更大的益处.
科学领域:
- 营养科学 营养科学
- 微生物学 微生物学
- 生物化学 生物化学
背景情况:
- 对健康至关重要,但在无机形式中通常吸收不良.
- 酒酵母将无机转化为可生物利用的有机形式.
- 甲 (SeM) 是丰富酵母的关键质量指标.
研究的目的:
- 评估丰富酵母中不同甲 (SeM) 含量对肠道微生物群的影响.
- 通过模拟人类消化过程的体外仿生胃肠反应器来评估影响.
- 为了将高SeM酵母与普通酵母和商业补充剂进行比较.
主要方法:
- 模拟酒酵母的消化,使用不同的SeM水平 (正常,中等,高) 和商业补充剂.
- 在体外仿生胃肠道反应器模型.
- 通过测序分析短链脂肪酸 (SCFA) 度和肠道微生物群组成.
主要成果:
- 与对照组和商业组相比,高SeM酵母显著增加了短链脂肪酸 (SCFA) 度 (p < 0.05).
- 微生物群分析显示,高SeM组中,细菌群和动菌菌的相对丰度增加.
- 观察到Firmicutes与Bacteroidetes的比率下降,这表明肠道代谢途径发生了显著变化.
结论:
- 含丰富的酵母含有高SeM水平,对肠道微生物群和SCFA生产有更有益的影响.
- 这些发现支持高SeM酵母对传统酵母和补充剂的增强健康益处.
- 为开发和应用丰富酵母在人类健康应用中提供了新的见解.
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