叶植物生物活性化合物的进步:调节与肥胖相关的慢性炎症
Jorge Barros1,2, Ana Abraão1, Irene Gouvinhas1
1Centre for Research and Technology of Agro-Environmental and Biological Sciences, CITAB, Inov4Agro, University of Trás-os-Montes and Alto Douro, UTAD, Quinta de Prados, 5000-801 Vila Real, Portugal.
International journal of molecular sciences
|April 17, 2025
概括
全球肥胖症正在上升,影响超过10亿人. 本综述探讨了特定食用植物中的生物活性化合物如何通过减少炎症和氧化应激来对抗肥胖.
科学领域:
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
- 分子生物学分子生物学
背景情况:
- 全球肥胖率正在上升,超过10亿人受到影响,死亡率显著.
- 肥胖是一种慢性疾病,涉及脂肪组织的改变,导致炎症和氧化应激.
- 亲炎性反应涉及B细胞,M1巨细胞和细胞因子失衡,而氧化应激涉及活性氧物种 (ROS).
研究的目的:
- 为了研究七种食用植物中的生物活性化合物:Annona cherimola,Ipomoea batata,Colocasia esculenta,Eriobotrya japonica,Cymbopogon citratus,Psidium guajava,和Smallanthus sonchifolius. 这两种植物中的生物活性化合物是什么?
- 评估这些植物化合物在缓解与肥胖有关的机制方面的潜力.
- 探索通过饮食和生活方式来管理肥胖的自然干预措施.
主要方法:
- 关于选定的食用植物及其生物活性化合物的科学文献的审查.
- 对这些化合物可能影响炎症和氧化应激的拟议机制的分析.
- 专注于可以减少促炎媒介和活性氧物种 (ROS) 的化合物.
主要成果:
- 选择的植物含有具有潜在抗炎和抗氧化特性的生物活性化合物.
- 这些化合物可能有助于调节免疫反应,从促炎状态转变为抗炎状态.
- 这些植物的饮食摄入量可能有助于减少与肥胖相关的氧化应激和细胞损伤.
结论:
- 像Annona cherimola和Psidium guajava这样的食用植物拥有生物活性化合物,可以为肥胖提供治疗益处.
- 生活方式的改变,包括富含这些植物化合物的饮食,可以通过减少炎症和氧化应激来帮助控制肥胖.
- 对这些植物衍生化合物的进一步研究是有必要的,以开发新的肥胖管理策略.
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