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相关概念视频

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

82
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
82
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

524
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
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Olfaction01:25

Olfaction

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
44.0K
Storage01:23

Storage

48
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze...
48

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相关实验视频

Updated: May 11, 2025

Horizontal Hippocampal Slices of the Mouse Brain
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海马会改变视觉表现来编码新的记忆.

Chenhui Liu1, Zhen Liu1, Kaiyuan Liu2

  • 1School of Life Science and Technology & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai 201210, China.

Cell reports
|April 17, 2025
PubMed
概括

研究人员确定了一组视觉皮层神经元组合,对记忆关联至关重要,依赖于海马. 海马激活有助于这一组合,揭示了早期记忆网络组织.

关键词:
科普:神经科学是什么意思协会学习协会学习英格拉姆 (Engram) 是一个电子书.在海马体内,海马体记忆 记忆 记忆 记忆 记忆视觉皮层 视觉皮层 视觉皮层

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相关实验视频

Last Updated: May 11, 2025

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科学领域:

  • 神经科学是一个神经科学.
  • 记忆研究 记忆研究
  • 系统神经科学 系统神经科学

背景情况:

  • 海马-皮层相互作用对于形成和存储情节性记忆至关重要.
  • 记忆编码期间这些相互作用的精确时间和机制尚未完全理解.

研究的目的:

  • 研究视觉皮层 (VIS) 在关联性学习和记忆形成中的作用.
  • 阐明海马对大脑皮层内记忆表征出现的贡献.

主要方法:

  • 在小鼠中利用了一种痕迹眼调节范式.
  • 运用光遗传学来操纵海马活动.
  • 使用成像和电生理学研究小鼠视觉皮层 (VIS) 中的神经元组合.
  • 检查了fOS+脑内图细胞和VIP+神经元在记忆编码中的作用.

主要成果:

  • 在VIS层II中确定了一个神经元组合,它对配对的有条件刺激 (CS) 和无条件刺激 (US) 作出反应,但不是离散的刺激.
  • 该协会的VIS表示依赖于海马,并有助于记忆编码.
  • 光遗传性海马激活促进了VIS中这种关联性表示的出现.
  • 发现由VIP+神经元调节的Fos+脑内细胞,在这个组合中充当枢纽.

结论:

  • 海马在早期学习阶段调节视觉皮层中的记忆合奏.
  • 在VIS中受到海马体影响的新兴记忆合集对于编码新关联至关重要.
  • 这突出了新记忆形成的记忆网络的结构组织.