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Updated: May 20, 2025

Identification of Nucleolar Factors During HIV-1 Replication Through Rev Immunoprecipitation and Mass Spectrometry
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核素识别MYC促进剂G-四重复的结构基础

Luying Chen1, Jonathan Dickerhoff1, Ke-Wei Zheng2

  • 1Borch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.

Science (New York, N.Y.)
|April 17, 2025
PubMed
概括

核蛋白与癌细胞中的MYC瘤基因促进体G-四重复 (MycG4) 结合. 这种对表观遗传调节至关重要的相互作用涉及多个结合域,并建议G-四重复作为药物发现的关键标.

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