雷多克斯双相稳定驱动的前药物策略,用于增强基于坎普托素的化疗:SN38的化作为一个案例研究

Junmin Xi1, Yu Liu1, Linjie Zhang2

  • 1School of Chemistry and Chemical Engineering, Nanjing University of Science & Technology, Nanjing, Jiangsu 210094, China.

Bioorganic chemistry
|April 17, 2025
PubMed
概括

一种含有的新型前药,Se-SN38,通过触发癌细胞中的氧化应激和亡,显示出增强的抗癌活性. 这种氧化还原激活策略为改善坎普托西因衍生疗法提供了一个有前途的方法.

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